Cosmelan Depigmentation Peel is a multi-ingredient chemical treatment. The first step is the cleansing and prepping of the skin. Then, the Cosmelan mask is applied in a thick layer. The mask must stay on between six and twelve hours depending on the level of correction needed. The Cosmelan mask is removed with a gentle, neutral cleanser and Mesoestetic Hydra-Vital Factor K is applied to comfort the skin and protect moisture. The second step of the procedure is the home care processes. Cosmelan II cream should be applied two to three times a day for two weeks after the first 14 days.